Researchers at Wayne State University, Detroit, found that differential patterns of DNA methylation in archived newborn blood may effectively detect infants exposed to at-risk maternal drinking, and predict lifelong behavioral expressions of Fetal Alcohol Spectrum Disorders. Using samples from the Michigan Neonatal Bank it was found that At-risk Prenatal Alcohol Exposure was associated with a set of significantly hypermethylated DNA sites in dried infant blood.  The degrees of DNA hypermethylation in many of these sites were correlated significantly with memory, behavior and fine motor problems in these children at age four.  These preliminary findings were part of a poster presentation titled, “DNA Methylation Changes in Neonatal Blood are Related to At-Risk Maternal Drinking Child Behavior” at the Society for Research in Child Development’s Biennial meeting.

Bulletin Board

  • The next meetings of the Community Values Advisory Board are scheduled for May 5 and September 8, 2014.

  • Michigan Neonatal Biobank has in excess of 2 million dry blood spot cards in inventory.

  • We thank the Carls Foundation for grants awarded to the Michigan Neonatal Biobank over the past three years.  Their generosity supported the expansion of the Biobank inventory.  

  • Nine Biobank Assistants have been accepted to Medical School during the past three years and six others are preparing for careers in medical related fields.

  • The Michigan Neonatal Biobank is a member of ISBER.

  • Seven research studies are currently using dried blood spots provided by the Michigan Neonatal Biobank. The studies center on some of the most intractable health issues for children: congenital heart defects, autism, cerebral palsy, spinal muscular atrophy and sudden infant death syndrome.

  • The Michigan BioTrust for Health is the Michigan Department of Community Health’s initiative to make leftover newborn screening samples more useful and available for approved medical or public health research.

  • The NIEHS announced  NOT-ES-14-002, a Notice of Intent to Publish an FOA for Children’s Environmental Health and Disease Prevention Research Centers (P01). Research teams that plan to respond to this RFA may find the samples at the MNBB to be a valuable core resource for a Center application.

?Visit us in both 1244 at the APHA Boston conference November 3 – 6.

Name: APHA Boston

Title: APHA Boston

Date: 10-28-13


♦Visit us in both 1244 at the APHA Boston conference November 3 – 6.

Biobank Images

2,000,000 blood spots 5

Funding Opportunities

fox2 allen nancy interview
FOX 2 Al Allen interview with Nancy Christ

Mike Brennan, Editor and Publisher interviews Michigan Neonatal Biobank Director Nancy Christ